Michaels Tips.

How to beat level 59.
Extra jokers will help on this level but are not necessary.

Part 1.

The key is removing cards that cover the 2 locked cards so you can plan a run that unlocks them and clears them even if you have to use your joker to do it.

Part 2. 

This is basically the same with 4 locked cards to uncover and use in a run. 

Locked cards in general take patience and planning. All levels are beatable without buying charms.